Find your "Hormone Sweet Spot".


Shoulder-Waist-Hip Ratio and Estrogen

As a Clinical Hormone Health Coach of over 15 years, I’ve had the privilege to witness thousands of women’s bodies make a physical transformation as they made their way to the “Hormone Sweet Spot” with the Panacea Protocol. One of the reasons I’m such a huge advocate of high dose estrogen therapies is because of how the physical body of a woman will do a reversal and restoration to as close to a reproductive aged woman to varying degrees because of estrogen levels. It’s no clinical secret that when women lose their estrogen, they lose their bodies as well. Even farmer’s know the best way to fatten up a sow is to remove the ovaries so pigs will stop producing estrogen and fatten up.

It is well documented that once women no longer produce “reproductive levels” of estrogen, her body (and mind) fall apart. Overall estradiol levels dictate what stage of life a woman is in. When estrogen is low, the brain thinks it’s time to check out and make way for the next generation and fat gets redistributed. When estrogen is not produced in healthy amounts in women no matter how old they are, fat mass increases and distribution changes. When estrogen is low, fat accumulates in the abdomen, upper arms, and back. In, addition, when estrogen is too low for too long, muscles will atrophy, tissues dehydrate, and bones get holes. The overall structure of the estrogen deficient female body is designed to deteriorate at a slow pace as fat in the belly, arms, and back increase.

When estrogen is in a particular range, meaning high enough but not too high, the brain of the woman thinks she’s in a state of reproduction so the body tries to replicate the shoulder-waist-hip ratio of a healthy reproductive female. Hormones are messengers, and when estrogen is too low, the brain and body responds in a negative way, when estrogen is sound, the brain and body also respond, but in a positive way.   When estrogen is sound, it’s a lot easier to lose fat for women. In addition, the muscle tone comes back and bones dense up for “reproductive purposes”, so the brain thinks. As estrogen is toning up muscles, the heart gets strong as well, as it too, is a muscle. This is why women get heart palpitations and shortness of breath when they get older with estrogen loss.

The goal is to get your hormones into a “Hormone Sweet Spot” so your brain and body won’t deteriorate or decline as it would without enough supercritical estrogen. You actually have the power to reshape your body with more control over your shoulder-waist-hip ratio if you get on the right HRT system prescribed in the right amounts and in the right way.

If you need help getting to your personal “Hormone Sweet Spot”, click on the button below and schedule a complementary consultation.

Tchernof A, Poehlman ET, Després JP. Body fat distribution, the menopause transition, and hormone replacement therapy. Diabetes Metab. 2000;26(1):12-20.

Fluctuating Hormones

Fluctuating Hormones. I read and hear a lot of people talking about “fluctuating” hormones and that the fluctuations are what cause the mood swings women of every age experience. The term fluctuate means to change continually; shift back and forth; vary irregularly. This appears to many that this is what hormones do but the reality is hormones are not irregular. They are produced in a rhythmic fashion like the rhythm of the ocean tides and on a schedule of sorts. The term rhythm means movement or procedure with uniform or patterned recurrence of a beat like music. These “rhythm tides” can be measured, timed, and controlled to relative degree. As you can see from the chart attached, each hormone has it’s own rhythm of sheet music. These hormone tide cycles are what people refer to as fluctuations. They are to really be looked at as rhythms on a schedule.

It’s important to understand the significance of this phenomenon because it plays a critical role in in your hormone health and why you feel so crappy, and it’s not what you think. It’s not the “fluctuations” or the ups and downs of the peaks and valleys of your hormones that cause such a mess mentally and physically at any age, but rather the flattening of those peaks is what causes extreme mental and physical symptomology that many woman get diagnosed with disorders and conditions like bi-polar, fibromyalgia, endometriosis, osteoporosis, anxiety, depression, PMDD, PMS, and thousands of other conditions women are told they have to live with.

There are two critical peaks between estrogen and progesterone’s hormone tide cycles that have to be optimally maintained in order for a woman to feel alive and well. The follicular peak of estrogen at Days 12-13 dictates how all other hormones, including progesterone, will produce and function the rest of the menstrual cycle, provided you have healthy functioning ovaries. This follicular peak of estrogen, if high enough, will up regulate receptors not only for estrogen, but progesterone and all other hormones so they perform at optimal functionality. When this happens, progesterone is able to make its peak high enough to down regulate estrogen receptors so the lining of the uterus will shed for an incident-free menstrual experience.

It’s important to maintain these rhythmic peaks, not flatten them out. When they flatten, nothing in the brain or body of a woman will feel right, and she will begin the living decaying process to death. It sounds dramatic but that’s what happens. Your estrogen levels send signals to the body as to where you are in the reproductive life stage process, and when estrogen is low and remains low, the mind of the female, no matter her age, will want to check out so to speak and the mind and body will fall apart. It is estrogen that dictates all of this. Women are least susceptible to mental and physical conditions when estrogen is maintained at optimal levels with healthy peaks for receptor up regulation. Without receptor up regulation nothing works right, just mental and physical misery.

If you’re having a hard time finding a doctor who understands this concept, click on the button below to make a complementary consultation.

Beauty Lies in the Beholder of Estrogen

She lingered for just a moment by the brook that runs through their family’s vineyard. I mustn’t risk discovery she pondered as she curled her toes into the sand warmed by the morning sun. Absence of the familiar boisterous noises flagged her memory. Ah yes, her brothers were out hunting, and wouldn’t be there to find her not tending to the young grape buds. I feel good, she mused to herself as her darkly sun bronzed legs carried her like a gazelle up the terraced hillside in search of her lover. Thoughts of her lover’s kiss danced lightly on the corners of her mind. Her body hungered for his attention and touch. “Oh that you would kiss me with the kisses of your mouth!”[2] “Oh that his left hand were under my head, and his right hand embraced me!”[3] “For your love is better than wine.”[4]

Her heart thrilled when she spotted her lover shepherding his flock for a drink down by the brook. No longer could she resist. Where have you been, my lover? “If you do not know, O fairest among women, following the flock.”[5] Hidden in this ancient text can be found the ageless notions of beauty, health, love and romance. It is a love story whose meaning will continue until the end of time.  

The desire to be beautiful is woven into the soul of every woman, and yet without estrogen there could be no feminine beauty, love, romance, passion, sexual desire, or procreation. Beauty, sex and estrogen lies at the epicenter of a woman’s ability to reap the rewards associated with beauty, good health, long life, sense of wellbeing, her capacity to establish meaningful emotional connections with others, and desire for sex.

Estrogen is the most ancient of all hormones.[6]  Even today, estrogen is critical to a woman’s body for a wide range of biologic processes. To achieve the distinction as “fairest of them all,” as king Solomon’s bride was, requires the convergence of multiple factors. Estrogen not only fashions the secondary sexual characteristics at puberty but also plays an important function at maintaining those characteristics throughout a woman’s life. How a woman looks, or how she feels has more to do with her estrogen production than any other single factor. This is why scrupulous attention to the factors responsible for optimal estrogen production is necessary for a woman to achieve her full biologic potential.

Thousands of physiological functions in the female body are directly dependent on estrogen for regulation. When estrogen goes missing there is a death signal propagated throughout her body heralding the start of a progressive downward spiral of deterioration. Long before she lays her ovaries in their final resting place she begins to experience distressing changes that rob her of health, beauty, joy, energy, sleep, memory, and sexual passion.

In the case of Solomon’s bride, she was molded in the finest crucible Mother Nature could provide. Hidden in the details of this ancient love story are clues to the factors necessary to assure optimal estrogen production. The best thing that could have befallen her, long before she became Solomon’s bride was to be relegated by her angry brothers to tend to their family’s vineyard. Their intent was to punish her, but it served a greater purpose of placing her in the best environment for fostering estrogen biosynthesis (how the ovaries produce estrogen).

In the case of vitamin D, its receptors are strategically expressed in the ovaries and play an important role in the regulation of estrogen biosynthesis.[7]  Exercise in the sun has a profound impact on physical and conformational development based on its impact on estrogen production. It turns out that “features of feminine beauty are associated with the highest estrogen levels.   Women with the highest levels of estrogen were rated as more attractive, healthier, and feminine looking than those with lower levels.”[8]  Puberty is a critical time in a woman’s development for establishing health and beauty. “These effects on appearance are likely to depend on the action of estrogen throughout puberty.”[9]

The combined insulin sensitizing effects of estradiol and vitamin D are instrumental in preventing obesity. Estradiol is a major determinant of body fat distribution, and promotes flat stomachs and sculpting of the gluteal and femoral region in ways that are pleasing to the eye. The influence of estradiol on body fat distribution appears to be related both to fat tissue specific expression of estrogen receptors and local tissue estrogen metabolism.[10]

On the other hand, estrogen is essential for the normal development, shape, tone, and function of the breast. Well-formed and perky breasts are the byproduct of sufficient estrogen, assuming adequate nutrition. Too often gravity is blamed for falling breasts when in actuality it is a symptom of declining estrogen.

When enough estrogen is present it blocks the deposition of fat in the fat cells of the stomach and trunk, while at the same time signaling the muscles to become more efficient at burning fat.[11] This important role of estrogen in determining regional body fat distribution not only results in the pleasing physical confirmation of the healthy female body, but also places her at 1/10th the risk as her male counterparts for developing cardiovascular disease.

Vitamin D, the mood boosting and feel good vitamin, is the precursor to a powerful steroid hormone that regulates the activation and deactivation of enzymes throughout the brain involved in the synthesis of neurotransmitters and nerve growth.[12]  Not only does vitamin D promote the biosynthesis of estradiol by the ovaries but also has a direct impact on neurotransmitter production, enhancing mood.

Additionally, estradiol has been recognized as an important neurotransmitter in the brain, but estradiol plays a critical role in the production of other neurotransmitters including the manufacture, release, reuptake and degradation of serotonin.[13] [14] [15]   Optimization of your estrogen production is one of the best defenses against symptoms of depression, anxiety or OCD. How a women looks and how she feels is critically dependent on her estrogen biosynthetic capacity.    

The capacity to feel spiritually grounded when life stressors seem over powering is the result of estrogen easing a woman’s stress response, and enabling her to take charge and effectively be the calm in the storm. When estrogen is at optimal levels a woman feels calm and she is much more inclined to pursue those spiritual quests that interest her.

“Upon my bed by night I sought him whom my soul loves; I sought him, but found him not; I called him, but he gave no answer. I will rise now and go about the city, in the streets and in the squares; I will seek him whom my soul loves. I sought him, but found him not. The watchman found me, as they went about the city. Have you seen him whom my soul loves? Scarcely had I passed them, when I found him whom my soul loves. I held him, and would not let him go until I had brought him into my mothers house, and into the chamber of her that conceived me.”[16]

Hardwired into the biology of every woman is the prime directive to transmit her genetic information. Whether she chooses to fulfill her prime directive is a personal choice. However, biology is destiny, and it is estrogen that transforms a woman into a fully operational reproductive female equipped with all the accouterments of sexual allure and armed not only with the capacity, but the passion to initiate a wide variety of mating rituals. The more completely estrogen can morph a woman into a work of perfection the more discriminating she can be in selecting her mate. Obviously, only the “fairest of them all” can seduce the heart of the prince, or in the case of Solomon’s bride, the King. What this means given the right environmental factors, estrogen can transform you into the best your genetic potential dictates.

In the healthy female, the desire for intercourse is primarily dictated by how much estrogen is produced. In accordance with the prime directive, the ultimate function of love, romance, and other courting rituals, as well as sex, is to propagate parental genes, and therefore reproduce the species. It is not primarily the desire to procreate, but sexual pleasure and the need to form emotional connections, facilitate bonding, and reduce sexual and interpersonal tensions, that are the prime motivators for sex. Without adequate estrogen, a woman perceives little to no need for sex. Without it, sex is no longer perceived as pleasurable, and for many, the idea of having sex becomes repulsive, leading to the avoidance of sexual intimacy all together.

The loss of sexual desire frequently leads to fractured relationships. Sex and sexual incompatibility was sited as the single most common contributing factor to divorce and is the catalyst behind 43 percent of all divorces.[17] The ability to produce estrogen is a function of how many eggs remain viable in the ovaries. As estrogen levels gradually diminish over time, 48% of women age 40 and older, never, or almost never have a spontaneous sexual thought, reflecting shifting priorities dictated by a woman’s declining egg count.

This is in stark distinction from those “sex crazed” teenagers, or those “overly sexed” college coed stereotypes of her younger years gone by. Even the female protagonist in the Song of Solomon exhibits a hungry desire for sexual intimacy with her lover. This can be ascribed to the natural outcome of possessing a healthy, fully loaded and operational reproductive system. At the most fundamental of levels humans can be defined as disposable DNA replicators imbued with the prime directive to pass on their genetic information to assure survival of the species. Both sexes are biologically invested in assuring the survival of our species and under ideal conditions exhibit comparable proclivities for sex and are equally libidinous.

If what you have just read doesn’t ring true with your own personal experience you’re not alone. Many features of modern civilization disrupt our endocrine function. Modern food consumption for example does not provide the nutritional elements necessary to support our basic physiology, nor does it have the nutritional power required to support the complexities of the female reproductive system. One reason our female protagonist developed sufficiently to be designated “the fairest of them all” was she grew up in a place once referred to as the “land flowing with milk and honey.” Not only was the soil rich and fertile, she ate an abundance of fruits and vegetables freshly harvested and organically grown from their family farm. She ingested plenty of protein, much of which came from freshly killed lamb, infused with omega 3 fatty acids. If your ovaries are to perform to their full potential, they require the best nutrition possible. Your ovaries will fail you in an environment of sugar, processed food and soda pop. Don’t expect to reap the full health and beauty benefits that estrogen can provide if your diet looks like the Standard American Diet.

In recent years estrogen’s reputation has been tarnished. Articles published in the last decade have women wary of anything that smacks of estrogen replacement. The trend by the media in recent years has been to pathologize estrogen and created fear and confusion among women and physicians alike. We have become so afraid of estrogen we have forgotten its central role in supporting every aspect of a woman’s health. When estrogen is balanced and nutritional optimization has been achieved, and there is sufficient fun in the sun, a woman’s body will function at peak efficiency. She will then reap the full benefits that estrogen was intended to supply.

If you’d like more information on how to get to your personal “Hormone Sweet Spot”, click on the button below and make a complementary consultation with me.

[1] The Song of Solomon 1:1 Revised Standard Version

[2] The Song of Solomon 1:1 Revised Standard Version

[3] The Song of Solomon 2:6 Revised Standard Version

[4] The Song of Solomon 1:2 Revised Standard Version

[5] The Song of Solomon 1:8 Revised Standard Version

[6] Trime, Susan, “Estrogen Emerges As Most Ancient of Hormones,” Columbia University Record, Vol 26 issue 21, May 7:2001

[7] Harkness LS, Bonny AE.   Calcium and vitamin D status: key roles for bone, body weight, glucose tolerance, and estrogen biosynthesis. J Pediatr Adolesc Gynecol. 2005 Oct; 18(5): 305-311.

[8] Vance, G. (2005). Hormone Levels Predict Attractiveness of Women. Retrieved from–hormone-levels-predict-attractiveness-of-women

[9] Vance, G. (2005). Hormone levels predict attractiveness of women. Retrieved from–hormone-levels-predict-attractiveness-of-women

[10] Mayes JS, Watson GH. 2004   Direct effects of sex steroid hormones on adipose tissue and obesity. Obes Rev 5:197-216.

[11] Mayes JS, Watson GH. 2004   Direct effects of sex steroid hormones on adipose tissue and obesity. Obes Rev 5:197-216.

[12] Welland, D.   Does vitamin D improve brain function?   New studies show low vitamin D may impair brain function: Scientific American Mind. 2009, Nov;

[13] Fink, G., et al. Estrogen control of central neurotransmission: Effect on mood, mental state, and memory. Cellular and Molecular Neurobiology. 1996; 16(3): 325-44.

[14] Halbreich, U., et al. Role of estrogen in postmenopausal depression. Neurology. 1997; 48(5): 516. Supplement 7.

[15] Studd, J., et al. Hormones and depression in women.   Climacteric. 2004; 7(4):338-46.

[16] The Song of Solomon 3:1-4 Revise Standard Version

[17] PRLog (Press Release) 2008 Sex Is Most Common Factor In Divorce

Misleading HRT Study

Screen Shot 2016-08-27 at 9.07.59 AMAnother misleading HRT study by The Pharmaceutical Journal about hormone replacement therapy (HRT) causing cancer. The only time estrogen causes cancer is when it’s kept too low. The problem with studies, articles, and reports like this one, is they throw all HRT in the same basket as if it’s all the same, and they do not conduct studies on the correct demographic of women. After reading the actual study, I failed to see where it was hormones that caused the cancer. When reading studies such as the one mentioned here, there are some things to take into consideration before coming to a conclusion as to whether the study is accurate: 

  1. What kind of hormones are they using? Not all HRT is the same. Hormone medicine has progressed over the last ten years especially with bioidentical hormones. There are four generations of HRT with the fifth generation under construction. Using first and second-generation hormones in a study is ridiculous and outdated. Bioidentical hormones are not the same as synthetic hormones.
  1. How are the hormones dosed? If the hormones given to patients are too low, then you’ll get nothing but a mess of problems. Merely treating the symptoms of hormone deficiency is not the same as truly dosing hormones to fix the problem of the deficiency, not just masking the symptoms of the deficiency. Hormones dosed to patients need to be high enough to trigger a receptor response. If this isn’t done, the patient will not be able to receive, utilize, and detoxify the hormones appropriately so the hormones get stored in the body creating problems. True hormone restoration involves restoring hormones back to healthy reproductive levels and you cannot do that with low dosing. Keeping hormones too low is a death sentence.
  1. In what manner are the hormones being dosed? Giving patients hormones in a static manner, especially low dosed estrogen eventually stops working after a short period of time because the dose is too low to trigger a receptor response for the hormones to work. Taking the same dose everyday does not mimic the natural physiology of a woman’s hormone tide-like cycle. It’s like being noseblind and the body won’t recognize them. Women (or men) do not produce hormones at the same amounts everyday. Estrogen has two peaks in a 28-day cycle with a high peak at Day 12 and another luteal not so high peak around Day 21. Dosing hormones in the natural physiologic rhythm of the male or female body allows for the production of receptors further allowing the body to properly receive, utilize, and detoxify hormones.
  1. How long has the patient been hormonally deficient? It’s impossible to resurrect the dead. The longer a patient has been hormonally deficient will determine how effective the hormone replacement will be. Using post menopausal women in a study where they’ve been so deficient for so long, already at significant risk for many deteriorating diseases, no amount of hormones can reverse or fix that. Estrogen decides how women feel mentally and physically and when women have been deficient for a while, they’re at increased risk of the degenerative diseases of aging. If you can catch women before they have one foot in the grave will keep women from going into menopause in the first place. The best time to address hormonal deficiencies is not after a woman has turned into a raisin, but when the decline begins, and that could be at any post menarche age. Many things cause estrogen to decline and most women have never had adequate amounts of estrogen due to many factors like birth control pills, medications, diet, lack of sleep when the sun is down, lack of physical movement, toxic exposure, etc. The birth control pill puts a woman in immediate chemical menopause. Take a moment to read the package insert of the birth control pill and read the warnings and side effects. You will read all the miserable things menopausal women experience because without estrogen, no matter how old a woman is, she will mentally feel like she’s going crazy and her physical body will fail. It’s a long, drawn out miserable living death. After a woman is finished having children is the best time to consider replacing hormones back to healthy levels to keep her brain and body from falling apart to begin with.
  1. What are the lifestyle factors involved? It’s never just about replacing hormones and calling it good. If a patient has a crappy diet, doesn’t sleep, taking a lot of meds, or doesn’t get physical activity in the sunshine and fresh air, they will never get the full benefits of the hormones. Taking hormones without addressing the other 15 Essential Elements of advanced hormone restoration will result in mediocre results. Patients feel better with HRT alone but the hormones work at an echelon level with combined with the right diet and lifestyle. What one puts in their body and how they live their life will determine the efficacy of the hormones. Hormone, only work well if taken in conjunction with a nutrient dense, whole foods, raw dairy diet, daily physical activity, and sleeping sound when the sun is down.

Most studies about HRT are misleading and keep women from seeking help. As long as our medical industry treats hormones, especially estrogen, as the enemy, women will feel like the walking dead. The biggest problem women face with HRT today is finding doctors who aren’t afraid of estrogen and who’re educated and trained in proper hormone restoration.


The Estrogen Cancer Myth

Screen Shot 2015-06-11 at 7.41.27 PMThe Estrogen Cancer Myth.  Is it real? Does estrogen really cause cancer?  There have been studies removed from the National Library of Medicine that give answers to estrogen-cancer questions.  This was done to keep people, doctors and patients, in the dark about hormones, estrogen and how to properly treat patients’ hormone deficiencies.  I was able to hire someone to locate a document in Europe by Robert Wilson, MD about estrogen and cancer.  Dr. Wilson is my hero and I aim to pick up where he left off. Below is the article kink and text of his article telling the truth about estrogen.

The Estrogen Cancer Myth


Clinical Medicine, August 1964, Brooklyn, NY

Although estrogens have been accused of causing cancer in women, the facts indicate that its administration actually offers hope of diminishing the incidence of malignant lesions including breast and genital cancer whatever the causative factors. Thus, estrogens should be administered postmenopausally.

Again and again, held in the same cell, the accused has faced the same charge. And with each imprisonment the Grand Jury, for lack of any but the most circumstantial evidence, has refused to indict. Released periodically, the accused has wandered friendless and alone, facing, until the next arrest, the suspicions, dread and hatred of most of the world. This has been going on for more than 20 years.

It is the story of estrogen.

In discussions with doctors and patients regarding the long term administration of estrogen, one question almost invariably arises: “But what about cancer?”

This is especially true in lay circles whenever the word hormone enters into the discussion. The literature regarding this aspect of estrogen is profuse and controversial, the confusion probably greatest in the etiology and treatment of breast cancer. It is not unusual to listen to an authority present the menace of estrogen and then terminate the meeting by showing slides of angry cancerous lesions melting away following estrogen administration. How did this paradoxical situation come about?

The Evidence

More than 20 years ago in the early days of cancer and hormone research (and they were largely contemporaneous) certain chemical substances administered to mice resulted in cancerous growths. These chemicals were therefore labeled “carcinogenic” and included many widely different substances among which were a few that also happened to be estrogenic. On this evidence is based, almost exclusively, the accusation that estrogens produce cancer. Mice are not humans, yet these results were heard around the world. The publicity has continued and has been devastating. A typical example is the blatant newspaper publicity given to more recent experiments with mice.

Special Strain

What is not generally known is that the mice used in the early experiments were a special strain which had been inbred for hundreds of generations. These mice had such a high incidence of spontaneous cancer that if they were allowed to live their natural lifetime under the best of conditions (no chemicals at all administered) more than 50% would develop mammary cancer. Certainly nothing is proven if 80 or 90% of such abnormal, unnaturally sensitive mice develop cancers after the administration of an estrogenic chemical. Injections of aspirin would undoubtedly be carcinogenic. What about dosage? These mice were given as much as 1 Gm. of the estrogenic chemical weekly for six months. However, a mouse weighs about 50 Gm. and lives only two years. Actually the susceptible mouse was given half its body weight for one fourth of its life span; it would be impossible to administer a proportionate amount to a woman even over a 20-year span. Is the attempt to translate these experiments into the human area anything but ludicrous?

Monkey Experiments

Attempts to obtain similar results with other animals have failed utterly. That estrogens are not carcinogenic in other animals was shown by investigators who assaulted monkeys for as long as 10 years with estrogens augmented by local trauma and other carcinogens. No malignant growths were produced. Still others administered massive doses of estrogens to Rhesus monkeys for as long as seven years; some received as much as one million rat units per year. There was not one instance of cancerous change in any organ. These experiments with monkeys are important because of the close relationship of monkey to man and are particularly valid in evaluating estrogens in humans. It has been reported that enormous doses of natural estrogens failed to produce new growths in rats and in a large number of human subjects. In spite of the inability of these and many other investigators to induce cancer by means of estrogen in any laboratory animal except the susceptible mouse, the stigma persists. This is indeed surprising, as there is no convincing proof that estrogen has ever induced cancer in the human being.

Normal Estrogen Levels

It is reassuring to realize that a woman has possessed and benefited from estrogen all her life, even long before birth. Her destiny is closely intertwined with it. There is further reassurance in the fact that she has the greatest amount of estrogenic hormone in her body between the years of 18 and 25 and yet during those years breast and genital cancer is at its lowest incidence. Cancer occurs most commonly when the female hormone level drops. Actually the incidence of cancer of all sites in women shows a constant increase with age, at the same time that the production of estrogen is steadily declining (high estrogen in youth-low incidence of cancer; low estrogen in age–high–incidence of cancer). The “dyed-in-the-wool” believer in the “estrogen menace” cannot explain these irrefutable facts, so he avoids them; he pretends they do not exist.

Estrogen Levels in Pregnancy

During the last few months of pregnancy, the placenta pours estrogen into the mother’s blood stream in astronomical amounts. The total estrogen produced during a normal menstrual cycle is about 5 mg. The amount produced in either of the last two months of pregnancy is almost 3000 mg.-an amount 600 times greater monthly than in her non-pregnant sister. At least 50 % of this tremendous amount passes freely into the fetus. There is increasing evidence that an adequate supply of estrogen is vital to the well being of the fetus. There is further evidence that the fetus, male or female, is itself actively concerned with estrogen synthesis. The full-term placenta contains about 51 mcg. of estrone, 170 mcg. of estradiol, and 315 mcg. of estriol per kilogram wet weight. It has been estimated that if the dose of an estrogen administered to a worn: an were 1.5 mg. weekly by injection (an average dose), it would require at least 125 times this amount weekly to approximate the state of pregnancy. If estrogen were carcinogenic, under these circumstances malignancy should be frequently encountered in pregnancy. Yet this is not so – it is relatively rare, only three per 10,000 pregnancies. Even in the occasional case encountered, the tumor may well have ante-dated the pregnancy.

Incidence of Cancer Unchanged

The incidence and mortality rate of breast cancer is the same today as in 1930 when estrogen was not in use. After Daisy’s discovery of estrogen more and more women have been treated by it so that at the present time in the United States it is safe to assume that more than 7,000,000 women consume estrogen with more or less regularity. The amount of estrogenic substance consumed yearly can thus be measured in tons. In view of the unchanged incidence of breast cancer during these years, how can one logically argue that estrogen causes cancer of the breast?

About 10,000 women die of cancer of the cervix in the United States each year. These deaths are at least 90% preventable. It is purely a question of detecting the cancer when it is localized, principally by cytological screening. The time is past when a patient should have to request that a cancer smear be taken; instead it should become so routine that she would believe she has not had a complete examination if it is omitted. By doing this, cancer of the cervix would, in most instances, be detected in its developing or pre-invasive (and thus curable) stages.

Many theories of the cause of cervical cancer have been explored but its cause is not known. Few physicians would implicate estrogen. The situation is rather to the contrary. It is a reasonable assumption that the maintenance of a healthy vaginal epithelium by local or systemic estrogen usage when needed would be cancer protective. An atrophic cervicitis is constantly trying to heal itself and it is under these circumstances of rapid cell growth that a cancer might develop. With hormonal treatment the atrophic cervicitis could have been prevented or cured and a cancer could conceivably have been prevented.

Endometrial Cancer

About 15,000 endometrial cancers occurred in the United States in 1963. Just as the anxieties of some regarding estrogens are concentrated primarily upon mammary tissue, so others are more concerned with the endometrium. They seem to ignore the fact that 92% of the cases of endometrial cancer occur after the age of 40 years when most estrogen levels are already decreased, are declining steadily, and when anywhere from 25 to 40% of the endometria are atrophic due to estrogen deficiency (maximum age of incidence is 57 years). The attempt to indict estrogen in this instance is indirect. Endometrial cancers are sometimes encountered simultaneously with endometrial hyperplasia. As hyperplasia is estrogen induced, therefore estrogen is the “cancer culprit”-guilt by association. A complicating factor is the extremely close microscopical similarity of endometrial adenocarcinoma and some forms of hyperplasia. It has been pointed out that there is no sharp line of demarcation between proliferative forms of hyperplasia and early adenocarcinoma. The growing use of progestogens and other steroids has further increased the risk of a mistake in diagnosis. One can only speculate upon the number of patients erroneously treated by irradiation, or hysterectomy, or both, and indexed in the hospital record room as endometrial carcinoma. The late Emil Novak who was intensely interested in this problem, concluded that the occurrence of the two entities is coincidental.

Cancer Prevention

As endometrial cancer is not a disease of the young except in the presence of ovarian failure to produce sufficient estrogen and progesterone, it is extremely important that the hypogonadal, premenopausal female be adequately treated. A logical inference is that if the menopause and the climacteric are prevented by the properly timed cyclic administration of estrogen and progesterone, this form of cancer will be simultaneously prevented. There is increasing evidence that exogenous progesterone and its analogues can produce a regressive effect on advanced and even disseminated endometrial cancer.

Quite apart from this direct effect there is another phenomenon which makes the continued growth of an endometrial cancer almost an impossibility, i.e. menstruation or withdrawal bleeding. Any in situ nest of atypical cells is inevitably uprooted and washed away in the deluge of debris, blood and fluids. This physical, cancer-controlling aspect of rhythmic uterine bleeding, whether natural or induced, has been almost completely overlooked by the profession. Induced postmenopausal bleeding need not necessarily be monthly; probably five or six times yearly is sufficient. Long needed has been an inexpensive practical method for the determination of a woman’s estrogen status. Recently a proven, simple technique was described in which, using a minor modification of the Papanicolaou smear; the percentages of superficial, intermediate and parabasal cells of the vaginal mucosa can be determined. These percentages in turn indicate the individual’s estrogen status.


Recently it was found in a large series of cases that the incidence of malignant lesions was three times greater in myxedematous patients than in those with highly active thyroid glands. Thus it appears that keeping a woman generally endocrinologically rich throughout her life, with the maintenance of adequate levels of estrogen and progesterone, offers hope of diminishing the incidence of malignant lesions including breast and genital cancer, whatever the causative factors (metabolic, receptive constitutions, heredity, viral, etc.) Such a concept inherently includes the elimination of the climacteric and the demolition of the “estrogen-cancer myth.”

This article has a PMID number of 15446202 for the National Library Medicine but the article has been removed so no one can get access to pro-estrogen studies.

The estrogen cancer debate has been a part of our history for years and it’s about time we put it to rest and give women their lives back.  You can read more about Dr. Wilson and his practice in his book Feminine Forever.

moxie script trans 75x75

1 2 3 6